Physical activity may reduce the risk of death from cardiovascular disease among American Indians, according to new research that also studied inflammation's role in exercise and heart health.
Past studies of people from all populations show that inflammation plays a central role in heart disease, and that exercise might reduce inflammation in the body.
For the new study, researchers focused on American Indians, "a special population that, unfortunately, is not always included in studies that show the benefit of physical activity," said the lead researcher Dr. Ozan Unlu, chief resident of quality and patient safety at Weill Cornell Medicine in New York City.
The findings will be presented Friday at the American Heart Association's virtual Scientific Sessions. The research is considered preliminary until published in a peer-reviewed journal.
The study looked at self-reported physical activity levels from 3,135 adults in Arizona, North Dakota, South Dakota and Oklahoma, who did not initially have cardiovascular disease and who took part in the Strong Heart Study of American Indians. Researchers also looked at their levels of fibrinogen, a blood plasma protein that is considered a marker for inflammation.
Researchers tracked the study's participants over 26 years of follow-up, during which 378 people died from heart disease. The groups were split into four equal groups, or quartiles. After adjusting for various factors, researchers found those who were the most physically active, in the top quartile, had a 44% lower risk of dying from cardiovascular disease than those in the bottom "minimal activity" quartile. The next two quartiles had a 31% and 9% lower death risk, respectively, than those in the lowest quartile.
"This study confirms that physical activity reduces cardiovascular mortality in this unique cohort of American Indians," Unlu said. "This is a population that doesn't always have the resources for exercise and physical activity that are available in urban settings."
The study's senior researcher, Dr. Parmanand Singh, said many of the participants live on reservations in rural areas where the nearest gym or other activity-related facility could be many miles away.
"We need to dig deeper and find out what sort of facilities can be constructed on reservations that are in line with the cultural value system of the population. We have to think about other interventions, too, such as bringing health fairs or other public health initiatives to the reservations," said Singh, assistant professor of medicine and director of nuclear cardiology at Weill Cornell Medicine.
The researchers looked at participants' fibrinogen levels and found "physical activity was possibly reducing cardiovascular deaths by inflammatory pathways," Unlu said.
The research was limited by its retrospective nature, Singh said. The findings need to be confirmed by future studies in which participants gradually get more physically active and researchers see if that impacts fibrinogen readings, he said.
Dr. Carl Lavie said the idea that exercise lowers fibrinogen levels and cardiovascular death rates "is nothing new, but the new thing is that in this American Indian population, the benefit of the physical activity is, at least statistically, explained by the lower fibrinogen." He is a medical director of cardiac rehabilitation, prevention and exercise at the Ochsner Clinical School/University of Queensland School of Medicine in New Orleans.
Lavie, who was not involved in the study, said more research is needed to figure out if fibrinogen is a valid way to measure cardiovascular risk. But even now, he said, "if one happened to measure a fibrinogen level and it was high, this would even provide further support for recommending physical activity."
Federal guidelines recommend adults get at least 150 minutes per week of moderate-intensity aerobic activity or 75 minutes per week of vigorous aerobic activity – or a combination of both.
Find more news from Scientific Sessions.
If you have questions or comments about this story, please email editor@heart.org.
American Heart Association News covers heart disease, stroke and related health issues. Not all views expressed in American Heart Association News stories reflect the official position of the American Heart Association.
Copyright is owned or held by the American Heart Association, Inc., and all rights are reserved. Permission is granted, at no cost and without need for further request, for individuals, media outlets, and non-commercial education and awareness efforts to link to, quote, excerpt or reprint from these stories in any medium as long as no text is altered and proper attribution is made to American Heart Association News.
Other uses, including educational products or services sold for profit, must comply with the American Heart Association’s Copyright Permission Guidelines. See full terms of use. These stories may not be used to promote or endorse a commercial product or service.
HEALTH CARE DISCLAIMER: This site and its services do not constitute the practice of medical advice, diagnosis or treatment. Always talk to your health care provider for diagnosis and treatment, including your specific medical needs. If you have or suspect that you have a medical problem or condition, please contact a qualified health care professional immediately. If you are in the United States and experiencing a medical emergency, call 911 or call for emergency medical help immediately.
"activity" - Google News
November 09, 2020 at 11:02PM
https://ift.tt/35btcwH
Physical activity could reduce heart disease deaths among American Indians - The Herald Review
"activity" - Google News
https://ift.tt/3ddCXMh
https://ift.tt/2WkO13c
Bagikan Berita Ini
Dewa HOKI lagi ada di pihak mu lo segera daftar dan bermain di DEWALOTTO kemenangan nyata menanti anda semua lo segera merapat ya guyss... :D
ReplyDeleteADD WA +855 888765575 Terima Kasih admint...:)